Patients with highest levels of the most powerful version of the immune molecule HLA-G appear to have the lowest risk of rejecting their transplanted kidney, researchers report. Physicians already examine HLA, or human leukocyte antigen, when identifying the best organ donor. When a patient and donor have the same or similar antigens, which are markers for what the body identifies as self and foreign, it increases the chance of a successful transplant.
This is Dr. Laura L. Mulloy, Chief of the MCG Section of Nephrology, Hypertension and Transplantation Medicine and Dr. Anatolij Horuzsko, immunologist both at the Medical College of Georgia at Georgia Regents University.